Concepedia

Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1

Min Zheng, Yanhai Wang, Xiaonan Wu, Suqin Wu, Bao-Ju Lu, Meng‐Qiu Dong, Hongbing Zhang, Peiqing Sun, Sheng‐Cai Lin, Kun‐Liang Guan,

Nature Cell Biology · 2011 · 139 citations · 40 references

DOIFull text

Open access

Concepts

References

40

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.2K citations

, , +17

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.9K citations · Full text

, , +10

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.8K citations · Full text

, , +15

mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

Do‐Hyung Kim, Dos D. Sarbassov, Siraj M. Ali et al. · Cell · 2002 · 3K citations · Full text

, , +14

A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

Jiahuai Han, Jeffrey Lee, L. Bibbs et al. · Science · 1994 · 2.7K citations

, , +13