Sequence-Specific Targeting of Duplex DNA Using a Camptothecin-Triple Helix Forming Oligonucleotide Conjugate and Topoisomerase I

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSequence-Specific Targeting of Duplex DNA Using a Camptothecin-Triple Helix Forming Oligonucleotide Conjugate and Topoisomerase IMark Matteucci, Kuei-Ying Lin, Teresa Huang, Richard Wagner, Daniel D. Sternbach, Mukund Mehrotra, and Jeffrey M. BestermanView Author Information Gilead Sciences, Inc., 333 Lakeside Drive Foster City, California 94404 Glaxo Wellcome Research Institute, Five Moore Drive Research Triangle Park, North Carolina 27709 Cite this: J. Am. Chem. Soc. 1997, 119, 29, 6939–6940Publication Date (Web):July 23, 1997Publication History Received27 January 1997Published online23 July 1997Published inissue 1 July 1997https://pubs.acs.org/doi/10.1021/ja9702475https://doi.org/10.1021/ja9702475rapid-communicationACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views219Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Conjugate acid-base pairs,Genetics,Modification,Peptides and proteins,Targeting Get e-Alerts