High-Resolution Crystal Structure of an Engineered Human β ₂ -Adrenergic G Protein–Coupled Receptor

Vadim Cherezov, Daniel M. Rosenbaum, Michael A. Hanson, +8

Science

Crystal structure of the β2 adrenergic receptor–Gs protein complex

Søren G. F. Rasmussen, Brian T. DeVree, Yaozhong Zou, +17

Nature

Molecular PharmacologyCrystal StructureBiochemistryG Protein-coupled ReceptorReceptor (Biochemistry) +4

Crystal structure of the human β2 adrenergic G-protein-coupled receptor

Søren G. F. Rasmussen, Hee‐Jung Choi, Daniel M. Rosenbaum, +10

Nature

Molecular PharmacologyCrystal StructureBiochemistryG Protein-coupled ReceptorMedicine +5

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Søren G. F. Rasmussen, Hee‐Jung Choi, Juan José Fung, +15

Nature

EngineeringNanomaterialsNanotechnologyNanobody-stabilized Active StateChemistry +1

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Aashish Manglik, Andrew C. Kruse, Tong Sun Kobilka, +7

Nature

Molecular Pharmacologyµ-Opioid Receptor BoundMorphinan AntagonistCrystal StructureBiochemistry +5

GPCR Engineering Yields High-Resolution Structural Insights into β ₂ -Adrenergic Receptor Function

Daniel M. Rosenbaum, Vadim Cherezov, Michael A. Hanson, +8

Science

The Dynamic Process of β2-Adrenergic Receptor Activation

Rie Nygaard, Yaozhong Zou, Ron O. Dror, +13

Cell

Molecular PharmacologyMolecular PhysiologySignal TransductionMedicinePhysiology +5

Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α ₂ -Adrenergic Receptor

Brian K. Kobilka, Hiroaki Matsui, Tong Sun Kobilka, +5

Science

Xenopus Laevis OocytesGeneticsPurified ReceptorMolecular PharmacologyAdrenal Gland +17

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

Aashish Manglik, Tae Hun Kim, Matthieu Masureel, +9

Cell

Molecular PharmacologyMolecular PhysiologySignal TransductionStructural InsightsG Protein-coupled Receptor +7

Structure of the δ-opioid receptor bound to naltrindole

Sébastien Granier, Aashish Manglik, Andrew C. Kruse, +4

Nature

Molecular PharmacologyMedicinePhysiologyMechanism Of ActionReceptor (Biochemistry) +4