An inhibitor of Janus kinase 2 prevents polycythemia in mice

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

Chloé James, Valérie Ugo, Jean‐Pierre Le Couedic et al. · Nature · 2005 · 3.5K citations

Hematological Malignancy, Signal Transduction, Receptor Tyrosine Kinase +9

A Gain-of-Function Mutation of <i>JAK2</i> in Myeloproliferative Disorders

Róbert Královics, Francesco Passamonti, Andreas Buser et al. · New England Journal of Medicine · 2005 · 3.4K citations · Full text

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

Ross L. Levine, Martha Wadleigh, Jan Cools et al. · Cancer Cell · 2005 · 3K citations · Full text

Hematological Malignancy, Polycythemia Vera, Essential Thrombocythemia +11

<i>JAK2</i> Exon 12 Mutations in Polycythemia Vera and Idiopathic Erythrocytosis

Linda M. Scott, Wei Tong, Ross L. Levine et al. · New England Journal of Medicine · 2007 · 1.2K citations · Full text

Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors

Evan Parganas, Demin Wang, Dimitrios J. Stravopodis et al. · Cell · 1998 · 1.2K citations · Full text

Inflammation, Cytokine, Signal Transduction +10