Johnny E. Kopinja

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

Douglas A. Rubinson, Christopher P. Dillon, Adam V. Kwiatkowski et al. · Nature Genetics · 2003 · 1.5K citations

Developmental Biology, Rna Interference, Lentivirus-based System +9

An orally available non-nucleotide STING agonist with antitumor activity

Bo‐Sheng Pan, Samanthi A. Perera, Jennifer Piesvaux et al. · Science · 2020 · 609 citations

Antitumor Activity, Immunology, Immunoediting +19

Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer

Wonsuk Chang, Michael D. Altman, Charles A. Lesburg et al. · Journal of Medicinal Chemistry · 2022 · 122 citations · Full text

Immunology, Molecular Biology, Interferon Genes +17

A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit

Johnny E. Kopinja, Raquel Sevilla, Diane Levitan et al. · Scientific Reports · 2017 · 51 citations · Full text

Cell Death, High-grade Gliomas, Cancer Biology +20

An inhibitor of Janus kinase 2 prevents polycythemia in mice

Anjili Mathur, Jan-Rung Mo, Manfred Kraus et al. · Biochemical Pharmacology · 2009 · 19 citations

Inflammation, Molecular Physiology, Medicine +9