Mixed polymeric micelles for combination cancer chemotherapy through the concurrent delivery of multiple chemotherapeutic agents

Design of Environment‐Sensitive Supramolecular Assemblies for Intracellular Drug Delivery: Polymeric Micelles that are Responsive to Intracellular pH Change

Younsoo Bae, Shigeto Fukushima, Atsushi Harada et al. · Angewandte Chemie International Edition · 2003 · 1.3K citations

Pharmacy, Pharmaceutics, Pharmacology +17

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

Edward H. Walker, Michael E. Pacold, Olga Perišić et al. · Molecular Cell · 2000 · 1.2K citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Block copolymer micelles as vehicles for drug delivery

Kazunori Kataoka, Kwon Glenn S., Okano Teruo et al. · Journal of Controlled Release · 1993 · 870 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +14

Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property:  Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy

Younsoo Bae, Nobuhiro Nishiyama, Shigeto Fukushima et al. · Bioconjugate Chemistry · 2004 · 732 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction

Matthias P. Wymann, Ginette Bulgarelli-Leva, Marketa Zvelebil et al. · Molecular and Cellular Biology · 1996 · 680 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16