Block copolymer micelles as vehicles for drug delivery

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Medicine, Oncology, Pharmacology +12

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

Donald R. Senger, Stephen J. Galli, Ann M. Dvořàk et al. · Science · 1983 · 4K citations

Medicine, Biochemistry, Oncology +13

Protein—surface interactions in the presence of polyethylene oxide

S.I Jeon, J.H Lee, Joseph D. Andrade et al. · Journal of Colloid and Interface Science · 1991 · 1.5K citations

Natural Sciences, Biochemistry, Materials Science +14

Poly(styrene-ethylene oxide) block copolymer micelle formation in water: a fluorescence probe study

Cheng Le Zhao, Yongcai Wang, Renliang Xu et al. · Macromolecules · 1991 · 1.3K citations

Natural Sciences, Chemistry, Materials Science +16

Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase.

Abraham Abuchowski, Judy McCoy, Nicholas C. Palczuk et al. · Journal of Biological Chemistry · 1977 · 1.3K citations · Full text

Life Sciences, Biochemistry, Immunology +14