Nobuhiro Nishiyama

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

Horacio Cabral, Yu Matsumoto, Kazue Mizuno et al. · Nature Nanotechnology · 2011 · 2.4K citations

Nanomedicine, Engineering, Permeable Tumours +8

Preparation and Biological Characterization of Polymeric Micelle Drug Carriers with Intracellular pH-Triggered Drug Release Property:  Tumor Permeability, Controlled Subcellular Drug Distribution, and Enhanced in Vivo Antitumor Efficacy

Younsoo Bae, Nobuhiro Nishiyama, Shigeto Fukushima et al. · Bioconjugate Chemistry · 2004 · 731 citations

Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice.

Nobuhiro Nishiyama, Souichiro Okazaki, Horacio Cabral et al. · PubMed · 2003 · 602 citations

Engineering, Solid Tumors, Biomedical Engineering +21

A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy

Peng Mi, Daisuke Kokuryo, Horacio Cabral et al. · Nature Nanotechnology · 2016 · 503 citations

Nanoparticles, Nanomedicine, Ph-activatable Nanoparticle +10

Lactosylated Poly(ethylene glycol)-siRNA Conjugate through Acid-Labile β-Thiopropionate Linkage to Construct pH-Sensitive Polyion Complex Micelles Achieving Enhanced Gene Silencing in Hepatoma Cells

Motoi Oishi, Yukio Nagasaki, Keiji Itaka et al. · Journal of the American Chemical Society · 2005 · 470 citations