Motoi Oishi

Lactosylated Poly(ethylene glycol)-siRNA Conjugate through Acid-Labile β-Thiopropionate Linkage to Construct pH-Sensitive Polyion Complex Micelles Achieving Enhanced Gene Silencing in Hepatoma Cells

Motoi Oishi, Yukio Nagasaki, Keiji Itaka et al. · Journal of the American Chemical Society · 2005 · 470 citations

Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid

Hiroto Hatakeyama, Hidetaka Akita, Kentaro Kogure et al. · Gene Therapy · 2006 · 393 citations

Cancer Therapy, Nanomedicine, Cell-based Drug Delivery +7

A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo

Hiroto Hatakeyama, Erika Ito, Hidetaka Akita et al. · Journal of Controlled Release · 2009 · 246 citations

Nanomedicine, Endosomal Escape, Molecular Biology +7

Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid

Hiroto Hatakeyama, Hidetaka Akita, Erika Ito et al. · Biomaterials · 2011 · 211 citations · Full text

Nanoparticles, Nanomedicine, Engineering +8

Smart PEGylated Gold Nanoparticles for the Cytoplasmic Delivery of siRNA to Induce Enhanced Gene Silencing

Motoi Oishi, Junpei Nakaogami, Takehiko Ishii et al. · Chemistry Letters · 2006 · 159 citations

Nanoparticles, Ethylene Glycol, Nanotherapeutics +16