A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

Horacio Cabral, Yu Matsumoto, Kazue Mizuno et al. · Nature Nanotechnology · 2011 · 2.4K citations

Pharmacy, Oncology, Pharmacokinetics +14

Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging

Jae‐Hyun Lee, Yong‐Min Huh, Young‐wook Jun et al. · Nature Medicine · 2006 · 1.9K citations · Full text

Natural Sciences, Biomedical Engineering, Materials Science +11

Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation

Gabriel Helmlinger, Fan Yuan, Marc Dellian · Nature Medicine · 1997 · 1.6K citations

Medicine, Cancer Biology, Oncology +9

A dual-emissive-materials design concept enables tumour hypoxia imaging

Guoqing Zhang, Gregory M. Palmer, Mark W. Dewhirst et al. · Nature Materials · 2009 · 1.1K citations · Full text

Medicine, Materials Science, Oncology +14

A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle

Moritz F. Kircher, Adam de la Zerda, Jesse V. Jokerst et al. · Nature Medicine · 2012 · 1.1K citations · Full text

Medicine, Biomedical Engineering, Oncology +17