Synthesis and biological evaluation of pyrazole derivatives containing thiourea skeleton as anticancer agents

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

Medicine, Genetics, Oncology +14

Studies of the HER-2/ <i>neu</i> Proto-Oncogene in Human Breast and Ovarian Cancer

Dennis J. Slamon, William Godolphin, Lovell A. Jones et al. · Science · 1989 · 6.9K citations

Medicine, Molecular Biology, Oncology +15

Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors:  Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1<i>H</i>-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

Thomas D. Penning, John J. Talley, Stephen R. Bertenshaw et al. · Journal of Medicinal Chemistry · 1997 · 2K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms <i>Haemophilus </i><i>i</i><i>nfluenzae</i> and <i>Moraxella </i><i>c</i><i>atarrhalis</i>

Michaël Génin, Debra A. Allwine, David Anderson et al. · Journal of Medicinal Chemistry · 2000 · 726 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors.

David K. Moscatello, Marina Holgado-Madruga, Andrew K. Godwin et al. · PubMed · 1995 · 641 citations

Medicine, Cancer Biology, Oncology +14