Marina Holgado-Madruga

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

Marina Holgado-Madruga, David R. Emlet, David K. Moscatello et al. · Nature · 1996 · 677 citations

Life Sciences, Biochemistry, Molecular Biology +14

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors.

David K. Moscatello, Marina Holgado-Madruga, Andrew K. Godwin et al. · PubMed · 1995 · 641 citations

Medicine, Cancer Biology, Oncology +14

Constitutive Activation of Phosphatidylinositol 3-Kinase by a Naturally Occurring Mutant Epidermal Growth Factor Receptor

David K. Moscatello, Marina Holgado-Madruga, David R. Emlet et al. · Journal of Biological Chemistry · 1998 · 304 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Christiane R. Maroun, Monica A. Naujokas, Marina Holgado-Madruga et al. · Molecular and Cellular Biology · 2000 · 287 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

Marina Holgado-Madruga, David K. Moscatello, David R. Emlet et al. · Proceedings of the National Academy of Sciences · 1997 · 277 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17