PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals

Sally E. Wenzel, Yulia Y. Tyurina, Jinming Zhao, +24

Cell

OxysterolLipid SynthesisBiochemistryPebp1 Wardens FerroptosisLipid Peroxidation +9

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

Marina Holgado-Madruga, David R. Emlet, David K. Moscatello, +2

Nature

Signal TransductionSignaling PathwayG Protein-coupled ReceptorMedicineDiabetes +4

Constitutive Activation of Phosphatidylinositol 3-Kinase by a Naturally Occurring Mutant Epidermal Growth Factor Receptor

David K. Moscatello, Marina Holgado-Madruga, David R. Emlet, +2

Journal of Biological Chemistry

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

Marina Holgado-Madruga, David K. Moscatello, David R. Emlet, +2

Proceedings of the National Academy of Sciences

Grb2-associated Binder-1 MediatesApoptosisCell DeathCellular PhysiologySignaling Pathway +14

Proteolytic Cleavage of the CD44 Adhesion Molecule in Multiple Human Tumors

Isamu Okamoto, Hiromasa Tsuiki, Lawrence C. Kenyon, +11

American Journal Of Pathology

Tumor BiologyProteolytic CleavageCd44 Adhesion MoleculeMedicineCell Adhesion +7

Targeting a Glioblastoma Cancer Stem-Cell Population Defined by EGF Receptor Variant III

David R. Emlet, Puja Gupta, Marina Holgado-Madruga, +9

Cancer Research

High-grade GliomasCancer BiologyGliomaTumor BiologyNeuro-oncology +14

Insulin-like growth factor binding protein 7 and tissue inhibitor of metalloproteinases-2: differential expression and secretion in human kidney tubule cells

David R. Emlet, Núria M. Pastor‐Soler, Allison L. Marciszyn, +6

American Journal of Physiology-Renal Physiology

ImmunologyCytoskeletonCellular PhysiologyProtein 7Renal Function +19

Expression of constitutively activated EGFRvlll in non‐small cell lung cancer

Isamu Okamoto, Lawrence C. Kenyon, David R. Emlet, +10

Cancer Science

Elevated JNK activation contributes to the pathogenesis of human brain tumors

Marc A. Antonyak, Lawrence C. Kenyon, Andrew K. Godwin, +7

Oncogene

Neuro-oncologySignaling PathwayMedicineNeuroscienceCell Biology +7

Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors.

Hiromasa Tsuiki, Mehdi Tnani, Isamu Okamoto, +7

PubMed

Primary Glial TumorsApoptosisPathologyCell DeathCancer Biology +20