Synthesis and biological evaluation of pyrazole derivatives containing thiourea skeleton as anticancer agents

Peng‐Cheng Lv, Huan‐Qiu Li, Juan Sun, +2

Bioorganic & Medicinal Chemistry

Medicinal ChemistryMedicineDrug DiscoveryPyrazole DerivativesPharmacological Agent +8

Synthesis and antiproliferative activity of indolizine derivatives incorporating a cyclopropylcarbonyl group against Hep-G2 cancer cell line

Yong‐Miao Shen, Peng‐Cheng Lv, Wu Chen, +3

European Journal of Medicinal Chemistry

EngineeringAntiproliferative ActivityMedicineOrganic ChemistryAnti-cancer Agent +6

Synthesis, biological evaluation and 3D-QSAR study of novel 4,5-dihydro-1H-pyrazole thiazole derivatives as BRAFV600E inhibitors

Mengyue Zhao, Yong Yin, Xiao‐Wei Yu, +7

Bioorganic & Medicinal Chemistry

Medicinal ChemistryBrafv600e InhibitorsMedicineNatural Sciences3D-qsar Study +7

Design, Synthesis, and Biological Evaluation of Potential Prodrugs Related to the Experimental Anticancer Agent Indotecan (LMP400)

Peng‐Cheng Lv, Mohamed Elsayed, Keli Agama, +3

Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryDrug-dna-top1 Ternary CleavageMedicineNatural Sciences +12

Novel 2,4,5-trisubstituted oxazole derivatives: Synthesis and antiproliferative activity

Xinhua Liu, Peng‐Cheng Lv, Jia‐Yu Xue, +2

European Journal of Medicinal Chemistry

Derivative (Chemistry)Antiproliferative ActivityOrganic ChemistryHeterocycle ChemistryPharmacology +1

Design, synthesis and evaluation of novel diaryl-1,5-diazoles derivatives bearing morpholine as potent dual COX-2/5-LOX inhibitors and antitumor agents

Zhang Li, Zhong‐Chang Wang, Xin Li, +9

European Journal of Medicinal Chemistry

Medicinal ChemistryAntitumor AgentsMedicinePharmacotherapyAnti-cancer Agent +6

Design, Synthesis, and Biological Evaluation of O-2-Modified Indenoisoquinolines as Dual Topoisomerase I–Tyrosyl-DNA Phosphodiesterase I Inhibitors

Peng‐Cheng Lv, Keli Agama, Christophe Marchand, +2

Journal of Medicinal Chemistry

Synthesis, molecular docking and biological evaluation of coumarin derivatives containing piperazine skeleton as potential antibacterial agents

She‐Feng Wang, Yong Yin, Xun Wu, +5

Bioorganic & Medicinal Chemistry

Combinatorial ChemistryBiochemistryMedicinePharmacologyAntibacterial Agent +6

Design, synthesis and biological evaluation of novel 5-phenyl-1H-pyrazole derivatives as potential BRAFV600E inhibitors

Shu-Fu Wang, Yinling Zhu, Pingting Zhu, +5

Bioorganic & Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBiochemistryMedicineNatural Sciences +9

Synthesis, Structure and Antibacterial Activity of Potent DNA Gyrase Inhibitors: N′-Benzoyl-3-(4-Bromophenyl)-1H-Pyrazole-5-Carbohydrazide Derivatives

Juan Sun, Peng‐Cheng Lv, Yong Yin, +3

PLoS ONE