Concepedia

Synthesis and evaluation of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors

B. Narasimhulu Naidu, Margaret E. Sorenson, Manoj Patel, Yasutsugu Ueda, Jacques Banville, Françis Beaulieu, Sagarika Bollini, Ira B. Dicker, Helen Higley, Zeyu Lin,

Bioorganic & Medicinal Chemistry Letters · 2014 · 48 citations · 7 references

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7

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Vincenzo Summa, Alessia Petrocchi, Fabio Bonelli et al. · Journal of Medicinal Chemistry · 2008 · 634 citations · Full text

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Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Brian A. Johns, Takashi Kawasuji, Jason G. Weatherhead et al. · Journal of Medicinal Chemistry · 2013 · 184 citations · Full text

, , +17

Quinolone Carboxylic Acids as a Novel Monoketo Acid Class of Human Immunodeficiency Virus Type 1 Integrase Inhibitors

Motohide Sato, Hiroshi Kawakami, Takahisa Motomura et al. · Journal of Medicinal Chemistry · 2009 · 108 citations · Full text

, , +16

The Molecular Biology of HIV Integrase

Robert Craigie · Future Virology · 2012 · 74 citations · Full text

, , +17

Facile One-Pot Synthesis of 2,3,5-Substituted 1,2,4-Oxadiazolines from Nitriles in Aqueous Solution

B. Narasimhulu Naidu, Margaret E. Sorenson · Organic Letters · 2005 · 38 citations

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