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Antagonistic effect of the cardioprotector (+)-1,2-BIS(3,5-dioxopiperazinyl-1-YL)propane(ICRF-187) on dna breaks and cytotoxicity induced by the topoisomerase ii directed drugs daunorubicin and etoposide (VP-16)

BiochemistryTopoisomerase IiMedicineMechanism Of ActionAntagonistic EffectPharmacotherapyDna BreaksAnti-cancer AgentCardiovascular ToxicityPharmacologyDrug DiscoveryDrug Resistance