G A Hofmann

In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone.

F H Drake, G A Hofmann, Shau Ming Mong et al. · PubMed · 1989 · 160 citations

Medicine, Oncology, Pharmacology +13

Synergistic cell killing by ionizing radiation and topoisomerase I inhibitor topotecan (SK&F 104864).

Michael R. Mattern, G A Hofmann, F L McCabe et al. · PubMed · 1991 · 149 citations

Medicine, Pharmacology, Radiation Oncology +17

Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content.

Wai-Kwong Eng, F L McCabe, K. B. Tan et al. · Molecular Pharmacology · 1990 · 127 citations

Medicine, Oncology, Pharmacology +14

Differences between normal and ras-transformed NIH-3T3 cells in expression of the 170kD and 180kD forms of topoisomerase II.

Richard Woessner, Theodore D. Chung, G A Hofmann et al. · PubMed · 1990 · 93 citations

Life Sciences, Biochemistry, Molecular Biology +9

In vitro and in vivo effects of clinically important camptothecin analogues on multidrug-resistant cells.

Michael R. Mattern, G A Hofmann, Rodd Polsky et al. · PubMed · 1993 · 92 citations

Medicine, Cancer Biology, Pharmacology +17