Michael R. Mattern

SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins

Michael P. Malakhov, Michael R. Mattern, Oxana A. Malakhova et al. · Journal of Structural and Functional Genomics · 2004 · 542 citations

Sumo Fusions, Protein Function, Protein Expression +10

Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells.

Richard Woessner, Michael R. Mattern, Christopher K. Mirabelli et al. · PubMed · 1991 · 462 citations

Chromatin, Cell Division, Biochemistry +12

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Priya Chaturvedi, Wai K Eng, Yuan Zhu et al. · Oncogene · 1999 · 423 citations

Chromatin, Genome Instability, Cell Regulation +8

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II

Fred H. Drake, Glenn A. Hofmann, H F Bartus et al. · Biochemistry · 1989 · 414 citations

Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Robert Hertzberg, Mary Jo Caranfa, Kenneth G. Holden et al. · Journal of Medicinal Chemistry · 1989 · 411 citations