Michael R. Mattern

SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins

Michael P. Malakhov, Michael R. Mattern, Oxana A. Malakhova et al. · Journal of Structural and Functional Genomics · 2004 · 550 citations

Life Sciences, Biochemistry, Molecular Biology +11

Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells.

Richard Woessner, Michael R. Mattern, Christopher K. Mirabelli et al. · PubMed · 1991 · 462 citations

Life Sciences, Cell Biology, Molecular Biology +14

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Priya Chaturvedi, Wai K Eng, Yuan Zhu et al. · Oncogene · 1999 · 424 citations

Life Sciences, Cell Biology, Molecular Biology +15

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II

Fred H. Drake, Glenn A. Hofmann, H F Bartus et al. · Biochemistry · 1989 · 414 citations

Medicine, Biochemistry, Pharmacology +9

Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Robert Hertzberg, Mary Jo Caranfa, Kenneth G. Holden et al. · Journal of Medicinal Chemistry · 1989 · 414 citations

Medicine, Medicinal Chemistry, Pharmacology +12