The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

Vito J. Palombella, Oliver J. Rando, Alfred L. Goldberg, +1

Cell

Transcriptional RegulationProtein FunctionSignal TransductionSignaling PathwayMolecular Pathway +12

A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein

Vincent Chau, John W. Tobias, Andreas Bachmair, +4

Science

Protein AssemblyGlycobiologyMolecular BiologyAnalytical UltracentrifugationMultiubiquitin Chain Is +19

A 26 S protease subunit that binds ubiquitin conjugates.

Quinn L. Deveraux, Vicença Ustrell, Cecile M. Pickart, +1

Journal of Biological Chemistry

Protein ChemistryProtein FunctionProtein AssemblyBiochemistryDifferent Subunits +8

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis.

Avram Hershko, Aaron Ciechanover, H Heller, +2

Proceedings of the National Academy of Sciences

Multiple ChainsProtein AssemblyProteasomeMolecular BiologyProtein Breakdown +16

Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain).

C P, Clive A. Slaughter, George Demartino

Journal of Biological Chemistry

The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

Feroz R. Papa, Mark Hochstrasser

Nature

MedicineGeneticsNatural SciencesGene StructureMolecular Biology +8

Proteasomes: destruction as a programme

Wolfgang Hilt, Dieter H. Wolf

Trends in Biochemical Sciences

Protein FunctionProtein FoldingNatural SciencesMedicineProteasome +4

Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.

Daniel Finley, Seth Sadis, Brett P. Monia, +4

Molecular and Cellular Biology

Fungal Cell BiologyGeneticsProteasomeMolecular BiologyMolecular Genetics +17

Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates

Avram Hershko, H Heller

Biochemical and Biophysical Research Communications

Protein ChemistryProtein FunctionProtein AssemblyNatural SciencesMolecular Biology +2

Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting.

R. W. Beal, Quinn L. Deveraux, Gui‐Yang Xia, +2

Proceedings of the National Academy of Sciences

Protein ChemistrySurface Hydrophobic ResiduesProtein FunctionProtein AssemblyBiochemistry +11