H Heller

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

Avram Hershko, H Heller, Sarah Elias et al. · Journal of Biological Chemistry · 1983 · 1.1K citations · Full text

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis.

Valery Sudakin, D Ganoth, Aviva Dahan et al. · Molecular Biology of the Cell · 1995 · 753 citations · Full text

Ubiquitin-mediated Degradation, Protein Function, Cell Regulation +15

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis.

Avram Hershko, Aaron Ciechanover, H Heller et al. · Proceedings of the National Academy of Sciences · 1980 · 738 citations · Full text

Multiple Chains, Protein Assembly, Proteasome +18

ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation.

Aaron Ciechanover, H Heller, Sarah Elias et al. · Proceedings of the National Academy of Sciences · 1980 · 537 citations · Full text

Apf-1 Conjugates, Proteasome, Molecular Biology +18

"Covalent affinity" purification of ubiquitin-activating enzyme.

Aaron Ciechanover, Sarah Elias, H Heller et al. · Journal of Biological Chemistry · 1982 · 314 citations · Full text