D Ganoth

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis.

Valery Sudakin, D Ganoth, Aviva Dahan et al. · Molecular Biology of the Cell · 1995 · 753 citations · Full text

Ubiquitin-mediated Degradation, Protein Function, Cell Regulation +15

ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin.

E Eytan, D Ganoth, T Armon et al. · Proceedings of the National Academy of Sciences · 1989 · 370 citations · Full text

Protein Chemistry, Atp-dependent Incorporation, Protein Function +15

ATP-dependent degradation of ubiquitin-protein conjugates.

Avram Hershko, E Leshinsky, D Ganoth et al. · Proceedings of the National Academy of Sciences · 1984 · 247 citations

Protein Chemistry, Protein Function, Atp-dependent Degradation +13

Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts.

Avram Hershko, D Ganoth, John R. Pehrson et al. · Journal of Biological Chemistry · 1991 · 243 citations · Full text

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

Avram Hershko, D Ganoth, Valery Sudakin et al. · Journal of Biological Chemistry · 1994 · 233 citations · Full text

Molecular Regulation, Molecular Biology, Cytoskeleton +18