Concepedia

Geriatric muscle stem cells switch reversible quiescence into senescence

Pedro Sousa‐Victor, Susana Gutarra, Laura García‐Prat, Javier Rodríguez‐Ubreva, Laura Ortet, Vanessa Ruiz‐Bonilla, Esteban Ballestar, Susana González, Antonio L. Serrano, Eusebio Perdiguero,

Nature · 2014 · 979 citations · 35 references

DOI

Concepts

References

35

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Darren J. Baker, Tobias Wijshake, Tamar Tchkonia et al. · Nature · 2011 · 3.6K citations · Full text

, , +13

Role of histone H2A ubiquitination in Polycomb silencing

Hengbin Wang, Liangjun Wang, Hediye Erdjument‐Bromage et al. · Nature · 2004 · 1.8K citations

, , +12

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Jacqueline J.L. Jacobs, Karin Kieboom, Silvia Marino et al. · Nature · 1999 · 1.6K citations

, , +13

Senescence in premalignant tumours

Manuel Collado, Jesús Gil, Alejo Efeyan et al. · Nature · 2005 · 1.5K citations

, , +12

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

Viktor Janzen, Randolf Forkert, Heather E. Fleming et al. · Nature · 2006 · 1.1K citations

, , +12