Concepedia

Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy

Yoshiaki Taniyama, Masahiro Ito, Kota Sato, C KUESTER, Kerstin Veit, Günter Tremp, Ronglih Liao, Wilson S. Colucci, Yuri Ivashchenko, Kenneth Walsh

Journal of Molecular and Cellular Cardiology · 2005 · 107 citations · 34 references

DOI

Concepts

References

34

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3.1K citations

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Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Han Cho, James Mu, Jason K. Kim et al. · Science · 2001 · 1.8K citations

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Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway

Brendan D. Manning, Andrew R. Tee, M. Nicole Logsdon et al. · Molecular Cell · 2002 · 1.6K citations · Full text

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Akt1/PKBα Is Required for Normal Growth but Dispensable for Maintenance of Glucose Homeostasis in Mice

Han Cho, Joanne L. Thorvaldsen, Qingwei Chu et al. · Journal of Biological Chemistry · 2001 · 963 citations · Full text

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Growth retardation and increased apoptosis in mice with homozygous disruption of the <i>akt1</i> gene

William S. Chen, Pei-Zhang Xu, Kathrin Gottlob et al. · Genes & Development · 2001 · 922 citations · Full text

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