Concepedia

New pathways from pteridines. Design and synthesis of a new class of potent and selective antitumor agents

Edward C. Taylor

Journal of Heterocyclic Chemistry · 1990 · 61 citations · 36 references

DOI

Concepts

References

36

Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin)

Sidney Farber, Louis K. Diamond, Robert D. Mercer et al. · New England Journal of Medicine · 1948 · 1.8K citations

, , +11

Chemistry and biology of pteridines 1986

John M. Scott · FEBS Letters · 1987 · 395 citations · Full text

, , +5

A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in mice

Terence R. Jones, A H Calvert, Ann L. Jackman et al. · European Journal of Cancer (1965) · 1981 · 239 citations

, , +7

A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesis

G. Peter Beardsley, Barbara A. Moroson, Edward C. Taylor et al. · Journal of Biological Chemistry · 1989 · 230 citations · Full text

, , +14

Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 clonal cell lines derived in vivo.

F. M. Sirotnak, D. M. Moccio, L. E. Kelleher et al. · PubMed · 1981 · 189 citations

, , +9