Terence R. Jones

A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in mice

Terence R. Jones, A H Calvert, Ann L. Jackman et al. · European Journal of Cancer (1965) · 1981 · 239 citations

Life Sciences, Medicinal Chemistry, Pharmacology +7

A phase I evaluation of the quinazoline antifolate thymidylate synthase inhibitor, N10-propargyl-5,8-dideazafolic acid, CB3717.

A H Calvert, D Alison, S. J. Harland et al. · Journal of Clinical Oncology · 1986 · 102 citations

Medicine, Pharmacology, Pharmacotherapy +7

A peptide derived from the non-receptor-binding region of urokinase plasminogen activator inhibits glioblastoma growth and angiogenesis <i>in vivo</i> in combination with cisplatin

Kazuhiko Mishima, Andrew P. Mazar, Allen M. Gown et al. · Proceedings of the National Academy of Sciences · 2000 · 90 citations · Full text

Medicine, Oncology, Pharmacology +16

Transcriptional Induction of the Urokinase Receptor Gene by a Constitutively Active Src

Heike Allgayer, Heng Wang, Gary E. Gallick et al. · Journal of Biological Chemistry · 1999 · 74 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Quinazoline antifolate thymidylate synthase inhibitors: alkyl, substituted alkyl, and aryl substituents in the C-2 position

Leslie R. Hughes, Ann L. Jackman, J.W. Oldfield et al. · Journal of Medicinal Chemistry · 1990 · 73 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6