Concepedia

A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis

Michael K. Cooper, Christopher A. Wassif, Patrycja A. Krakowiak, Jussi Taipale, Ruoyu Gong, Richard I. Kelley, Forbes D. Porter, Philip A. Beachy

Nature Genetics · 2003 · 398 citations · 28 references

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28

Functional rafts in cell membranes

Kai Simons, Elina Ikonen · Nature · 1997 · 9.7K citations

, , +14

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

Chin Chiang, Ying Litingtung, Eric Lee et al. · Nature · 1996 · 3.1K citations

, , +14

Altered Neural Cell Fates and Medulloblastoma in Mouse <i>patched</i> Mutants

Lisa V. Goodrich, Ljiljana Milenković, Kay M. Higgins et al. · Science · 1997 · 1.7K citations

, , +17

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

James Chen, Jussi Taipale, Michael K. Cooper et al. · Genes & Development · 2002 · 1.5K citations · Full text

, , +13

Cholesterol Modification of Hedgehog Signaling Proteins in Animal Development

Jeffery A. Porter, Keith E. Young, Philip A. Beachy · Science · 1996 · 1.4K citations

, , +16