Concepedia

Discovery of Specific Inhibitors of Human USP7/HAUSP Deubiquitinating Enzyme

Céline Reverdy, Susan Conrath, Roman Lopez, Cécile Planquette, Cédric Atmanène, Vincent Collura, Jane Harpon, Véronique Battaglia, Valérie Vivat, Wolfgang Sippl,

Chemistry & Biology · 2012 · 267 citations · 31 references

DOI

Concepts

References

31

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

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In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

, , +15

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

Byung‐Hoon Lee, Min Jae Lee, Soyeon Park et al. · Nature · 2010 · 932 citations · Full text

, , +13

A Dynamic Role of HAUSP in the p53-Mdm2 Pathway

Muyang Li, Christopher Brooks, Ning Kon et al. · Molecular Cell · 2004 · 671 citations · Full text

, , +9

Crystal Structure of a UBP-Family Deubiquitinating Enzyme in Isolation and in Complex with Ubiquitin Aldehyde

Min Hu, Pingwei Li, Muyang Li et al. · Cell · 2002 · 644 citations · Full text

, , +14