Concepedia

Dithiocarbamate Toxicity toward Thymocytes Involves Their Copper-Catalyzed Conversion to Thiuram Disulfides, Which Oxidize Glutathione in a Redox Cycle without the Release of Reactive Oxygen Species

Mark J. Burkitt, Hugh S. Bishop, Lesley Milne, Shui Ying Tsang, Gordon J. Provan, Stefan Nobel, Sten Orrenius, Andrew F.G. Slater

Archives of Biochemistry and Biophysics · 1998 · 122 citations · 54 references

DOI

Concepts

References

54

The Chemical Basis of Radiation Biology

P. O’Neill · International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine · 1987 · 1.8K citations

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Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

Ralf Schreck, Beate Meier, Daniela N. Männel et al. · The Journal of Experimental Medicine · 1992 · 1.5K citations · Full text

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The Role of Glutathione in Copper Metabolism and Toxicity

Jonathan H. Freedman, Maria Rosa Ciriolo, J. Peisach · Journal of Biological Chemistry · 1989 · 593 citations · Full text

, , +15

Generation of Superoxide Free Radical during the Autoxidation of Thiols

Hara P. Misra · Journal of Biological Chemistry · 1974 · 561 citations · Full text

, , +15

In the absence of catalytic metals ascorbate does not autoxidize at pH 7: ascorbate as a test for catalytic metals

Garry R. Buettner · Journal of Biochemical and Biophysical Methods · 1988 · 509 citations

, , +11