Concepedia

Glutathione System

The Glutathione System is a biochemical defense mechanism, belonging to the class of cellular antioxidant systems, that is distinguished by its reliance on glutathione—a tripeptide thiol compound—and associated enzymes such as glutathione peroxidase and glutathione reductase to maintain redox homeostasis and detoxify reactive oxygen species.

10.2K

Publications

625.6K

Citations

33.8K

Authors

5K

Institutions

Publications per year

2017–2026

1.1K

Parents

Publications

10.2K

Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.

Donald E. Paglia, William N. Valentine · PubMed · 1967 · 10.8K citations

, , +14

Selenium: Biochemical Role as a Component of Glutathione Peroxidase

John T. Rotruck, A. L. Pope, Howard E. Ganther et al. · Science · 1973 · 7.8K citations

, , +16

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

Frank Tietze · Analytical Biochemistry · 1969 · 6.1K citations

, , +14

ASCORBATE AND GLUTATHIONE: Keeping Active Oxygen Under Control

Graham Noctor, Christine H. Foyer · Annual Review of Plant Physiology and Plant Molecular Biology · 1998 · 5.7K citations

, , +17

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

Owen W. Griffith · Analytical Biochemistry · 1980 · 4.6K citations

, , +6

1–5 of 10.2K

Authors

33.8K

  1. BM
    Bengt Mannervik

    Uppsala University, Sweden

    94 publications · 13K citations

    47

    h-index

  2. GF
    Giorgio Federici

    University of Rome Tor Vergata, Italy

    46 publications · 2.6K citations

    27

    h-index

  3. HS
    Helmut Sies

    Heinrich Heine University Düsseldorf, Germany

    35 publications · 5.5K citations

    27

    h-index

  4. BK
    B Ketterer

    Courtauld Institute of Art, United Kingdom

    33 publications · 2.8K citations

    26

    h-index

  5. DP
    Dean P. Jones

    Emory University, United States

    33 publications · 3.8K citations

    26

    h-index

1–5 of 33.8K

Institutions

5K

  1. Cornell University

    Ithaca, United States

    60 h-index

    261 publications

    41.5K citations

  2. Karolinska Institutet

    Stockholm, Sweden

    50 h-index

    364 publications

    24.8K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    46 h-index

    294 publications

    18.6K citations

  4. Emory University

    Atlanta, United States

    43 h-index

    233 publications

    23.9K citations

  5. University of Washington

    Seattle, United States

    41 h-index

    269 publications

    15.6K citations

  6. The University of Texas Medical Branch at Galveston

    Galveston, United States

    38 h-index

    274 publications

    12.9K citations

  7. University of Southern California

    Los Angeles, United States

    37 h-index

    162 publications

    19.1K citations

  8. University of Rome Tor Vergata

    Rome, Italy

    36 h-index

    295 publications

    16.1K citations

1–8 of 5K

Venues

  1. Journal of Biological Chemistry

    JBC · 197 publications · 28.7K citations

    91

    h-index

  2. PubMed

    Repository · 611 publications · 40.5K citations

    84

    h-index

  3. Biochemical Pharmacology

    284 publications · 15K citations

    64

    h-index

  4. Free Radical Biology and Medicine

    179 publications · 11.6K citations

    61

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 179 publications · 10.5K citations

    60

    h-index

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