Concepedia

Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines – Lessons for design of combination targeted therapy

Brian Park, Zakary L. Whichard, Seth J. Corey

Cancer Letters · 2012 · 43 citations · 39 references

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39

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

Andrea Bild, Guang Yao, Jeffrey T. Chang et al. · Nature · 2005 · 2.1K citations

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

Poulikos I. Poulikakos, Chao Zhang, Gideon Bollag et al. · Nature · 2010 · 1.8K citations · Full text

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Breast Tumor Cell Lines From Pleural Effusions2

Relda Cailleau, Russell K. Young, Matilde Olivé et al. · JNCI Journal of the National Cancer Institute · 1974 · 1K citations · Full text

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Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism

Xiaolin Wan, B Harkavy, Patrick J. Grohar et al. · Oncogene · 2006 · 747 citations

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Overexpression of the EGF receptor‐related proto‐oncogene erbB‐2 in human mammary tumor cell lines by different molecular mechanisms.

M H Kraus, N.C. Popescu, Suzanne C. Amsbaugh et al. · The EMBO Journal · 1987 · 619 citations · Full text

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