Concepedia

Targeted Therapy Development

Targeted Therapy Development is a translational research endeavor that involves the design and optimization of therapeutic agents or strategies specifically directed at molecular or cellular targets implicated in cancer pathogenesis, distinguishing it from broad-spectrum treatment approaches by its precision and mechanism-based focus.

245

Publications

12.3K

Citations

1.7K

Authors

588

Institutions

Publications per year

2017–2026

92

Parents

Publications

245

Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial

Christophe Le Tourneau, Jean-Pierre Delord, Anthony Gonçalvès et al. · The Lancet Oncology · 2015 · 1.1K citations

, , +14

Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial

Toni K. Choueiri, Susan Halabi, Ben L. Sanford et al. · Journal of Clinical Oncology · 2017 · 715 citations

, , +14

Analyses of repeated failures in cancer therapy for solid tumors: poor tumor‐selective drug delivery, low therapeutic efficacy and unsustainable costs

Hiroshi Maeda, Mahin Khatami · Clinical and Translational Medicine · 2018 · 486 citations · Full text

, , +16

An <i>In vivo</i> Platform for Translational Drug Development in Pancreatic Cancer

Belén Rubio‐Viqueira, Antonio Jimeno, George Cusatis et al. · Clinical Cancer Research · 2006 · 412 citations · Full text

, , +16

Translating cancer research into targeted therapeutics

Johann S. de Bono, Alan Ashworth · Nature · 2010 · 338 citations

, , +12

1–5 of 245

Authors

1.7K

  1. RS
    Roy S. Herbst

    The University of Texas MD Anderson Cancer Center, United States

    4 publications · 271 citations

    4

    h-index

  2. MC
    Mario Coccia

    National Research Council, Italy

    3 publications · 92 citations

    3

    h-index

  3. MD
    Murray D. Norris

    Children's Cancer Institute Australia, Australia

    3 publications · 88 citations

    3

    h-index

  4. CM
    Chelsea Mayoh

    UNSW Sydney, Australia

    3 publications · 88 citations

    3

    h-index

  5. MH
    Michelle Haber

    Children's Cancer Institute Australia, Australia

    3 publications · 88 citations

    3

    h-index

1–5 of 1.7K

Institutions

588

  1. Harvard University

    Cambridge, United States

    14 h-index

    56 publications

    3.4K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    13 h-index

    106 publications

    6.6K citations

  3. National Cancer Institute

    Bethesda, United States

    12 h-index

    37 publications

    1.7K citations

  4. Dana-Farber Cancer Institute

    Boston, United States

    11 h-index

    60 publications

    12.7K citations

  5. Massachusetts General Hospital

    Boston, United States

    8 h-index

    13 publications

    558 citations

  6. Inserm

    Paris, France

    8 h-index

    17 publications

    3.1K citations

  7. Memorial Sloan Kettering Cancer Center

    New York, United States

    7 h-index

    26 publications

    2.8K citations

  8. National Institutes of Health

    Bethesda, United States

    6 h-index

    12 publications

    757 citations

1–8 of 588

Venues

  1. PubMed

    Repository · 23 publications · 693 citations

    15

    h-index

  2. Clinical Cancer Research

    10 publications · 806 citations

    10

    h-index

  3. Scientific Reports

    7 publications · 342 citations

    7

    h-index

  4. Cancer Research

    6 publications · 357 citations

    6

    h-index

  5. Oncotarget

    5 publications · 157 citations

    5

    h-index

1–5