Concepedia

Patrick J. Grohar

PJ

34

Publications

2.2K

Citations

20

H-Index

1999

Active since

Affiliations

Children's Hospital of Philadelphia(Current)

Van Andel Institute

Center for Cancer Research

National Cancer Institute

University of Pennsylvania

Patrick J. Grohar is an author at Children's Hospital of Philadelphia specializing in medicine, cell biology, and pathology.

ORCID

Top concepts

Publications per year

1999–2024

34

Publications

34

Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism

Xiaolin Wan, B Harkavy, Patrick J. Grohar et al. · Oncogene · 2006 · 745 citations

, , +8

Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

Patrick J. Grohar, Girma M. Woldemichael, Laurie B. Griffin et al. · JNCI Journal of the National Cancer Institute · 2011 · 202 citations · Full text

Ecteinascidin 743 Interferes with the Activity of EWS-FLI1 in Ewing Sarcoma Cells

Patrick J. Grohar, Laurie B. Griffin, Choh Yeung et al. · Neoplasia · 2011 · 121 citations · Full text

Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus

Matt L. Harlow, Nichole Maloney, Joseph T. Roland et al. · Cancer Research · 2016 · 87 citations · Full text

, , +13

Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth

Patrick J. Grohar, Laure E. Segars, Choh Yeung et al. · Clinical Cancer Research · 2013 · 83 citations · Full text

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