Patrick J. Grohar

Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism

Xiaolin Wan, B Harkavy, Patrick J. Grohar et al. · Oncogene · 2006 · 747 citations

Life Sciences, Biochemistry, Molecular Biology +12

Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

Patrick J. Grohar, Girma M. Woldemichael, Laurie B. Griffin et al. · JNCI Journal of the National Cancer Institute · 2011 · 204 citations · Full text

Medicine, Oncology, Pharmacology +14

Ecteinascidin 743 Interferes with the Activity of EWS-FLI1 in Ewing Sarcoma Cells

Patrick J. Grohar, Laurie B. Griffin, Choh Yeung et al. · Neoplasia · 2011 · 123 citations · Full text

Medicine, Molecular Biology, Oncology +17

Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus

Matt L. Harlow, Nichole Maloney, Joseph T. Roland et al. · Cancer Research · 2016 · 92 citations · Full text

Medicine, Molecular Biology, Oncology +14

Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth

Patrick J. Grohar, Laure E. Segars, Choh Yeung et al. · Clinical Cancer Research · 2013 · 86 citations · Full text

Medicine, Oncology, Pharmacology +17