NK1.1 Cells Express 4-1BB (CDw137) Costimulatory Molecule and Are Required for Tumor Immunity Elicited by Anti-4-1BB Monoclonal Antibodies

RAG-1-deficient mice have no mature B and T lymphocytes

Peter Mombaerts, John Iacomini, Randall S. Johnson et al. · Cell · 1992 · 2.9K citations

Life Sciences, Genetics, Immunology +13

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

Ignacio Melero, Walter W. Shuford, S A Newby et al. · Nature Medicine · 1997 · 891 citations

Life Sciences, Immunology, Oncology +14

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

Walter W. Shuford, Kerry Klussman, Douglas D. Tritchler et al. · The Journal of Experimental Medicine · 1997 · 792 citations · Full text

Life Sciences, Cell Biology, Immunology +17

CELL SURFACE IMMUNOGLOBULIN

Ellen S. Vitetta, Sonia Baur, Jonathan W. Uhr · The Journal of Experimental Medicine · 1971 · 378 citations · Full text

Life Sciences, Cell Biology, Immunology +9

4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB

Robert H. Arch, Craig B. Thompson · Molecular and Cellular Biology · 1998 · 354 citations · Full text

Life Sciences, Immunology, Molecular Biology +12