Concepedia

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

Chen Yao, Rabih El Khoury, Wen Wang, Tara A. Byrd, Elizabeth A. Pehek, Colin Thacker, Xiongwei Zhu, Mark A. Smith, Amy L. Wilson‐Delfosse, Shu G. Chen

Neurobiology of Disease · 2010 · 149 citations · 31 references

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31

Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

Alexander Zimprich, Saskia Biskup, Petra Leitner et al. · Neuron · 2004 · 3.1K citations · Full text

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Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease

Coro Paisán-Ruı́z, Shushant Jain, E. Whitney Evans et al. · Neuron · 2004 · 2.4K citations · Full text

, , +14

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

Andrew B. West, Darren J. Moore, Saskia Biskup et al. · Proceedings of the National Academy of Sciences · 2005 · 1.2K citations · Full text

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C. elegans Locomotory Rate Is Modulated by the Environment through a Dopaminergic Pathway and by Experience through a Serotonergic Pathway

Elizabeth R. Sawin, Rajesh Ranganathan, H. Robert Horvitz · Neuron · 2000 · 1.1K citations · Full text

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Kinase activity of mutant LRRK2 mediates neuronal toxicity

Wanli W. Smith, Zhong Pei, Haibing Jiang et al. · Nature Neuroscience · 2006 · 623 citations

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