Chen Yao

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

Chen Yao, Rabih El Khoury, Wen Wang et al. · Neurobiology of Disease · 2010 · 145 citations · Full text

Neurodegenerative Diseases, Lrrk2-mediated Neurodegeneration, Dopaminergic Neurons +8

Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells

Min‐Bin Chen, Yan Zhang, Mu-Xin Wei et al. · Cellular Signalling · 2013 · 109 citations

Amp-activated Protein Kinase, Medicine, Growth Inhibition +9

MicroRNA‐124‐3p regulates cell proliferation, invasion, apoptosis, and bioenergetics by targeting PIM1 in astrocytoma

Danni Deng, Lei Wang, Chen Yao et al. · Cancer Science · 2016 · 77 citations · Full text

Cell Death, Cell Proliferation, Cancer Biology +17

Pterostilbene Attenuates Early Brain Injury Following Subarachnoid Hemorrhage via Inhibition of the NLRP3 Inflammasome and Nox2-Related Oxidative Stress

Haixiao Liu, Lei Zhao, Bodong Wang et al. · Molecular Neurobiology · 2016 · 70 citations

Inflammation, Nox2-related Oxidative Stress, Medicine +10

Vitamin B12 modulates Parkinson’s disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection

Adam Schaffner, Xianting Li, Yacob Gómez-Llorente et al. · Cell Research · 2019 · 66 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Allosteric Regulation +10