A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication

Chiara Tyndall, Girolama La Mantia, Colin Thacker, +2

Nucleic Acids Research

Viral ReplicationEarly Gene ExpressionGeneticsMolecular BiologyMolecular Genetics +17

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

Chen Yao, Rabih El Khoury, Wen Wang, +7

Neurobiology of Disease

Neurodegenerative DiseasesLrrk2-mediated NeurodegenerationDopaminergic NeuronsCaenorhabditis Elegans ModelNeurotransmitter +6

A Putative Cation Channel and Its Novel Regulator: Cross-Species Conservation of Effects on General Anesthesia

John A. Humphrey, Kevin S.C. Hamming, Colin Thacker, +5

Current Biology

OptogeneticsGeneral AnesthesiaPutative Cation ChannelNeurophysiologyMedicine +12

UNC-80 and the NCA Ion Channels Contribute to Endocytosis Defects in Synaptojanin Mutants

Maëlle Jospin, Shigeki Watanabe, Deepa Joshi, +6

Current Biology

Molecular NeuroscienceMolecular PhysiologySignal TransductionMedicineNatural Sciences +10

The bli-4 locus of Caenorhabditis elegans encodes structurally distinct kex2/subtilisin-like endoproteases essential for early development and adult morphology.

Colin Thacker, Kirsten E. Peters, Martin Srayko, +1

Genes & Development

Bli-4 LocusGeneticsDistinct Kex2/subtilisin-like EndoproteasesGene CharacterizationMolecular Genetics +16

Neuronal Activity and CaMKII Regulate Kinesin-Mediated Transport of Synaptic AMPARs

Frédéric J. Hoerndli, Rui Wang, Jerry E. Mellem, +5

Neuron

Synaptic PlasticityNeuromuscular JunctionMolecular PhysiologySignal TransductionMolecular Neuroscience +13

The<i>C. elegans</i>T-type calcium channel CCA-1 boosts neuromuscular transmission

Katherine A. Steger, Boris B. Shtonda, Colin Thacker, +2

Journal of Experimental Biology

Muscle FunctionSynaptic TransmissionT-type Calcium ChannelMechanotransductionNeurotransmission +19

HIF-1 Regulates Iron Homeostasis in Caenorhabditis elegans by Activation and Inhibition of Genes Involved in Iron Uptake and Storage

Steven Joshua Romney, Ben S. Newman, Colin Thacker, +1

PLoS Genetics

Critical Residues of the<i>Caenorhabditis elegans unc-2</i>Voltage-Gated Calcium Channel That Affect Behavioral and Physiological Properties

Eleanor Mathews, Esperanza Garcı́a, Celia M. Santi, +4

Journal of Neuroscience

Synaptic TransmissionGeneticsNeurotransmitterNeurotransmissionCritical Residues +26

Caenorhabditis elegans dpy-5 is a cuticle procollagen processed by a proprotein convertase

Colin Thacker, Jonathan A. Sheps, Ann M. Rose

Cellular and Molecular Life Sciences

Proprotein ConvertaseProtein FunctionDevelopmental BiologyNatural SciencesMolecular Biology +8