Amy L. Wilson‐Delfosse

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

Xinglong Wang, Hisashi Fujioka, Jinyue Liu et al. · Human Molecular Genetics · 2012 · 417 citations · Full text

The Parkinson’s disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase thatstimulates kinase activity

Luxuan Guo, Payal N. Gandhi, Wen Wang et al. · Experimental Cell Research · 2007 · 208 citations · Full text

Neurodegenerative Diseases, Signal Transduction, Neurobiology Of Disease +11

The Roc domain of leucine‐rich repeat kinase 2 is sufficient for interaction with microtubules

Payal N. Gandhi, Xinglong Wang, Xiongwei Zhu et al. · Journal of Neuroscience Research · 2008 · 169 citations · Full text

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

Chen Yao, Rabih El Khoury, Wen Wang et al. · Neurobiology of Disease · 2010 · 145 citations · Full text

Neurodegenerative Diseases, Lrrk2-mediated Neurodegeneration, Dopaminergic Neurons +8

Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

Chang Yao, William M. Johnson, Yuan Gao et al. · Human Molecular Genetics · 2012 · 74 citations · Full text

Lrrk2 Toxicity, Apoptosis, Kinase Inhibitors +21