Neurobiology of Disease · 2014 · 79 citations · 44 references
Life SciencesNeurobiologyNeuroscienceMolecular NeurobiologyMolecular NeuroscienceNeurodegenerationDopaminergic SignalingLong-term DepressionMolecular Basis Of NeurodegenerationNeurodegenerative DiseasesNeurodegenerative DisordersParkinson DiseaseDepression In Parkinson's DiseaseDopaminergic NeuronsDopaminergic NeurophysiologyDopaminergic Synaptic DysfunctionLrrk2 MutationsTransgenic Mouse Models
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Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology
Alexander Zimprich, Saskia Biskup, Petra Leitner et al. · Neuron · 2004 · 3.1K citations · Full text
Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease
Coro Paisán-Ruı́z, Shushant Jain, E. Whitney Evans et al. · Neuron · 2004 · 2.4K citations · Full text
A common LRRK2 mutation in idiopathic Parkinson's disease
William P. Gilks, Patrick M. Abou‐Sleiman, Sonia Gandhi et al. · The Lancet · 2005 · 778 citations · Full text
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
Elisa Greggio, Shushant Jain, Ann E. Kingsbury et al. · Neurobiology of Disease · 2006 · 748 citations · Full text
Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic
Qun‐Yong Zhou, Richard D. Palmiter · Cell · 1995 · 734 citations · Full text