Elisa Greggio

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

Elisa Greggio, Shushant Jain, Ann E. Kingsbury et al. · Neurobiology of Disease · 2006 · 748 citations · Full text

Life Sciences, Cell Biology, Toxicology +15

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

Alexandria Beilina, Iakov N. Rudenko, Alice Kaganovich et al. · Proceedings of the National Academy of Sciences · 2014 · 367 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation

Elisa Greggio, Ibardo Zambrano, Alice Kaganovich et al. · Journal of Biological Chemistry · 2008 · 317 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +13

The R1441C mutation of LRRK2 disrupts GTP hydrolysis

Patrick A. Lewis, Elisa Greggio, Alexandra Beilina et al. · Biochemical and Biophysical Research Communications · 2007 · 277 citations · Full text

Life Sciences, Genetics, Molecular Biology +5

Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1

Jeff Blackinton, Mahadevan Lakshminarasimhan, Kelly Jean Thomas Craig et al. · Journal of Biological Chemistry · 2009 · 275 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13