Mahadevan Lakshminarasimhan

Ex-527 inhibits Sirtuins by exploiting their unique NAD ⁺ -dependent deacetylation mechanism

M. Gertz, Frank Fischer, Giang Thi Tuyet Nguyen et al. · Proceedings of the National Academy of Sciences · 2013 · 304 citations · Full text

Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1

Jeff Blackinton, Mahadevan Lakshminarasimhan, Kelly Jean Thomas Craig et al. · Journal of Biological Chemistry · 2009 · 274 citations · Full text

Reductive Stress, Protein Function, Aldehyde Dehydrogenase +14

An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms

David Rauh, Frank Fischer, M. Gertz et al. · Nature Communications · 2013 · 204 citations · Full text

Protein Function, Functional Genomics, Protein Expression +10

Cysteine p<i>K</i>_a Depression by a Protonated Glutamic Acid in Human DJ-1

Anna C. Witt, Mahadevan Lakshminarasimhan, Benjamin C. Remington et al. · Biochemistry · 2008 · 140 citations · Full text

Sirt1 activation by resveratrol is substrate sequence-selective

Mahadevan Lakshminarasimhan, David Rauh, Mike Schutkowski et al. · Aging · 2013 · 115 citations · Full text