Concepedia

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

Elisa Greggio, Shushant Jain, Ann E. Kingsbury, Rina Bandopadhyay, Patrick A. Lewis, Alice Kaganovich, Marcel P. van der Brug, Alexandra Beilina, Jeff Blackinton, Kelly Jean Thomas Craig,

Neurobiology of Disease · 2006 · 748 citations · 18 references

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18

Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

Alexander Zimprich, Saskia Biskup, Petra Leitner et al. · Neuron · 2004 · 3.1K citations · Full text

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Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease

Coro Paisán-Ruı́z, Shushant Jain, E. Whitney Evans et al. · Neuron · 2004 · 2.4K citations · Full text

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Montserrat Arrasate, Siddhartha Mitra, Erik S. Schweitzer et al. · Nature · 2004 · 2K citations

, , +15

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

Andrew B. West, Darren J. Moore, Saskia Biskup et al. · Proceedings of the National Academy of Sciences · 2005 · 1.2K citations · Full text

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A new locus for Parkinson's disease (<i>PARK8</i>) maps to chromosome 12p11.2–q13.1

Manabu Funayama, Kazuko Hasegawa, Hisayuki Kowa et al. · Annals of Neurology · 2002 · 667 citations

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