Alexandra Beilina

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

Elisa Greggio, Shushant Jain, Ann E. Kingsbury et al. · Neurobiology of Disease · 2006 · 742 citations · Full text

Mutant Lrrk2/dardarin, Signal Transduction, Signaling Pathway +11

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

Kelly Jean Thomas Craig, Melissa K. McCoy, Jeff Blackinton et al. · Human Molecular Genetics · 2010 · 446 citations · Full text

Dj-1 Acts, Mitophagy, Genetics +18

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

Alexandra Beilina, Marcel van der Brug, Rili Ahmad et al. · Proceedings of the National Academy of Sciences · 2005 · 378 citations · Full text

Mitophagy, Genetics, Molecular Biology +16

The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation

Elisa Greggio, Ibardo Zambrano, Alice Kaganovich et al. · Journal of Biological Chemistry · 2008 · 313 citations · Full text

The R1441C mutation of LRRK2 disrupts GTP hydrolysis

Patrick A. Lewis, Elisa Greggio, Alexandra Beilina et al. · Biochemical and Biophysical Research Communications · 2007 · 271 citations · Full text

R1441c Mutation, Biochemical Genetics, Biochemistry +1