Dietary selenium intake influences Cx43 dephosphorylation, TNF‐α expression and cardiac remodeling after reperfused infarction

Abstract

Dietary selenium intake influences post-infarct cardiac remodeling even when provided within the range of physiological values. Our data suggest that the cardioprotective effect of selenium might be mediated by a reduced oxidative stress, a lower connexin-43 dephosphorylation, and a decreased TNF-α expression.