Liangwei Zhong

Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence

Liangwei Zhong, Elias S.J. Arnér, Arne Holmgren · Proceedings of the National Academy of Sciences · 2000 · 517 citations

Life Sciences, Biochemistry, Molecular Biology +16

Essential Role of Selenium in the Catalytic Activities of Mammalian Thioredoxin Reductase Revealed by Characterization of Recombinant Enzymes with Selenocysteine Mutations

Liangwei Zhong, Arne Holmgren · Journal of Biological Chemistry · 2000 · 425 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Three-dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine-dependent enzyme

Tatyana Sandalova, Liangwei Zhong, Ylva Lindqvist et al. · Proceedings of the National Academy of Sciences · 2001 · 342 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Preparation and assay of mammalian thioredoxin and thioredoxin reductase

Elias S.J. Arnér, Liangwei Zhong, Arne Holmgren · Methods in enzymology on CD-ROM/Methods in enzymology · 1999 · 320 citations

Life Sciences, Biochemistry, Molecular Genetics +10

Rat and Calf Thioredoxin Reductase Are Homologous to Glutathione Reductase with a Carboxyl-terminal Elongation Containing a Conserved Catalytically Active Penultimate Selenocysteine Residue

Liangwei Zhong, Elias S.J. Arnér, Johanna Ljung et al. · Journal of Biological Chemistry · 1998 · 264 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8