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Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage

Jongho Park, Seong Won Lee, Seung Wook Yang, Hee Min Yoo, Jung Mi Park, Min Woo Seong, Seung Hyeun Ka, Kyu Hee Oh, Young Joo Jeon, Chin Ha Chung

Nature Communications · 2014 · 42 citations · 41 references

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41

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein et al. · Nature · 2000 · 3.5K citations

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RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO

Carsten Hoege, Boris Pfander, George‐Lucian Moldovan et al. · Nature · 2002 · 2.2K citations

, , +9

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

Heidi A. Tissenbaum, Leonard Guarente · Nature · 2001 · 1.9K citations

, , +10

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

Jason G. Wood, Blanka Rogina, Siva Lavu et al. · Nature · 2004 · 1.9K citations

, , +16

Requirement of NAD and <i>SIR2</i> for Life-Span Extension by Calorie Restriction in <i>Saccharomyces cerevisiae</i>

Su-Ju Lin, Pierre‐Antoine Defossez, Leonard Guarente · Science · 2000 · 1.8K citations

, , +17