Pierre‐Antoine Defossez

Requirement of NAD and <i>SIR2</i> for Life-Span Extension by Calorie Restriction in <i>Saccharomyces cerevisiae</i>

Su-Ju Lin, Pierre‐Antoine Defossez, Leonard Guarente · Science · 2000 · 1.8K citations

Life Sciences, Genetics, Molecular Biology +17

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

Su-Ju Lin, Matt Kaeberlein, Alex A. Andalis et al. · Nature · 2002 · 1.1K citations

Life Sciences, Biology, Physiology +14

Elimination of Replication Block Protein Fob1 Extends the Life Span of Yeast Mother Cells

Pierre‐Antoine Defossez, Reeta Prusty, Matt Kaeberlein et al. · Molecular Cell · 1999 · 414 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

A Family of Human Zinc Finger Proteins That Bind Methylated DNA and Repress Transcription

Guillaume J. Filion, Svetlana Zhenilo, Daisuke Yamada et al. · Molecular and Cellular Biology · 2005 · 353 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation

Laure Ferry, Alexandra Fournier, Takeshi Tsusaka et al. · Molecular Cell · 2017 · 194 citations · Full text

Life Sciences, Genetics, Molecular Biology +11