The signalling profile of recombinant human orexin-2 receptor

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

Steffan N. Ho, Henry D. Hunt, Robert M. Horton et al. · Gene · 1989 · 7.5K citations

Life Sciences, Biotechnology, Molecular Biology +10

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

Ling Lin, Juliette Faraco, Robin Li et al. · Cell · 1999 · 2.6K citations · Full text

Medicine, Neurology, Neuroscience +13

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Christelle Peyron, Juliette Faraco, William M. Rogers et al. · Nature Medicine · 2000 · 2.1K citations

Life Sciences, Neurology, Neuroscience +13

Differential expression of orexin receptors 1 and 2 in the rat brain

Jacob Marcus, Carl Aschkenasi, Charlotte E. Lee et al. · The Journal of Comparative Neurology · 2001 · 1.7K citations

Life Sciences, Neurobiology, Neuroscience +12

Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A

Yehia Daaka, Louis M. Luttrell, Robert J. Lefkowitz · Nature · 1997 · 1.3K citations

Life Sciences, Biochemistry, Pharmacology +16