Concepedia
Chemistry & Biology · 2013 · 169 citations · 48 references
MedicineGeneticsMolecular GeneticsGene ExpressionCystic FibrosisCftr Gene MutationsCftr Protein FunctionPathogenic Variant Correction
48
Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations
Life Sciences, Genetics, Molecular Genetics +12
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
F. Niesen, H. Berglund, Masoud Vedadi · Nature Protocols · 2007 · 2.4K citations
Life Sciences, Biochemistry, Biophysics +14
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
Gerene M. Denning, Matthew P. Anderson, Jane F. Amara et al. · Nature · 1992 · 1.2K citations
Life Sciences, Genetics, Molecular Biology +9
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809
Fredrick Van Goor, Sabine Hadidaꝉ, Peter D. J. Grootenhuis et al. · Proceedings of the National Academy of Sciences · 2011 · 1.1K citations · Full text
Medicine, Molecular Biology, Pharmacology +13
Q-SiteFinder: an energy-based method for the prediction of protein-ligand binding sites
Alasdair T. R. Laurie, Robert M. Jackson · Computer applications in the biosciences · 2005 · 1.1K citations · Full text
Pharmacy, Bioinformatics, Medicinal Chemistry +17