Concepedia

EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis

Weiwei Yang, Yan Xia, Yu Cao, Yanhua Zheng, Wen Bu, Lin Zhang, M. James You, Mei Yee Koh, Gilbert J. Cote, Kenneth Aldape,

Molecular Cell · 2012 · 243 citations · 25 references

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25

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

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Prognostic and predictive factors in breast cancer by immunohistochemical analysis.

D. Craig Allred, Jennet Harvey, Melora D. Berardo et al. · PubMed · 1998 · 2.2K citations

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

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NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

Jordi Rius, Mónica Gumá, Christian Schachtrup et al. · Nature · 2008 · 1.6K citations · Full text

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Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

Weibo Luo, Hongxia Hu, Ryan Chang et al. · Cell · 2011 · 1.4K citations · Full text

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