Wen Bu

Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms

Ik Sun Kim, Yang Gao, Thomas Welte et al. · Nature Cell Biology · 2019 · 329 citations

Breast Oncology, Cancer Immunosurveillance, Breast Cancer Reveals +11

Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer

Na Zhao, Jin Cao, Longyong Xu et al. · Journal of Clinical Investigation · 2018 · 254 citations · Full text

Tumor Biology, Oncogenic Myc, Systems Biology +14

EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis

Weiwei Yang, Yan Xia, Yu Cao et al. · Molecular Cell · 2012 · 241 citations · Full text

Tumor Biology, Medicine, Receptor Tyrosine Kinase +10

A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells

Yan Zhang, Dandan Lv, Ha-Jeong Kim et al. · Cell Research · 2012 · 117 citations · Full text

Immunology, Myeloid-derived Suppressor Cells, Novel Role +10

Breast tumor cell-specific knockout of <i>Twist1</i> inhibits cancer cell plasticity, dissemination, and lung metastasis in mice

Yixiang Xu, Dong-Kee Lee, Zhen Feng et al. · Proceedings of the National Academy of Sciences · 2017 · 116 citations · Full text

Breast Cancer Metastasis, Breast Oncology, Cancer Cell Plasticity +16